Chromium-51 is the radioisotope of the chemical element chromium, which, in addition to the element-specific 24 protons, has 27 neutrons in the atomic nucleus, resulting in the mass number 51.
See also: list of Chromium isotopes.
Chromium-51 decays radioactively by electron capture and emitting gamma rays (0.320 MeV).
Half-life T½ = 27.704(4) d respectively 2.3936256 × 106 seconds s.
Decay mode | Daughter | Probability | Decay energy | γ energy (intensity) |
---|---|---|---|---|
EC | 51V | 100 % | 0.75239(19) MeV | 0.3200835(4) MeV 9.91(1) % |
Direct parent isotope is: 51Mn.
The radionuclide chromium-51 has been used as a tracer in radiomedicine for decades. As a radiodiagnostic, it is used in nephrology to determine the glomerular filtration rate and in hematology to determine the volume or mass of red blood cells, to study the survival time of red blood cells and to assess blood loss. Corresponding 51Cr radiopharmaceuticals include:
- Chromium (51Cr) edetate (renal system, ATC-Code V09CX04),
- Chromium (51Cr) chromate labelled cells (cardiovascular system, ATC V09GX03). This includes e.g. B. sodium (51Cr) chromate.
More recently, reports have appeared indicating a decline in the use of Cr-51 preparations and the search for alternative radioisotopes for the stated uses [1].
Z | Isotone N = 27 | Isobar A = 51 |
---|---|---|
11 | 38Na | |
12 | 39Mg | |
13 | 40Al | |
14 | 41Si | |
15 | 42P | |
16 | 43S | |
17 | 44Cl | 51Cl |
18 | 45Ar | 51Ar |
19 | 46K | 51K |
20 | 47Ca | 51Ca |
21 | 48Sc | 51Sc |
22 | 49Ti | 51Ti |
23 | 50V | 51V |
24 | 51Cr | 51Cr |
25 | 52Mn | 51Mn |
26 | 53Fe | 51Fe |
27 | 54Co | 51Co |
28 | 55Ni | 51Ni |
29 | 56Cu | |
30 | 57Zn | |
31 | 58Ga | |
32 | 59Ge |
[0] - Research articles in scientific journals via PubMed: Chromium-51.
[1] - J. Dinet et al.:
Discontinuation of Chromium-51 for clinical use: What are the possible alternatives for radiopharmacies and nuclear medicine departments?.
In: Annales Pharmaceutiques Françaises, (2020), DOI 10.1016/j.pharma.2020.01.006.
Last update: 2023-10-04
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