4-Hydroxynorephedrine (also para- or p-Hydroxynorephedrine, PHN) is an organic chemical compound from the group of hydroxy analogues of norephedrine and an active sympathomimetic metabolite of amphetamine in humans.
Systematic name
4-[(1R,2S)-2-Amino-1-hydroxypropyl]phenol
Other names, synonyms
p-Hydroxynorephedrine; para-Hydroxynorephedrine; (-)-4-Hydroxynorephedrine; (1R,2S)-2-Amino-1-(4-hydroxyphenyl)propan-1-ol
Abbreviation
PHN
Latin name
Phenylpropanolaminum
Molecular formula and structural formula of 4-Hydroxynorephedrine:
C9H13NO2
Mr = 167.208 g/mol
4-[(1R,2S)-2-Amino-1-hydroxypropyl]phenol
SMILES: C[C@@H]([C@@H](C1=CC=C(C=C1)O)O)N
Calculated NMR spectrum (Predict Spectra via NMRDB)
1H NMR Spektrum, 13C NMR Spektrum.
Mass-related elemental composition and isotope proportions of the compound 4-Hydroxynorephedrine - C9H13NO2 - calculated based on molecular mass.
*) The third column lists the atomic masses or isotope masses of the elements involved and - in square brackets - the natural isotope composition.
The molar mass is M = 167.208 grams per mole.
The amount of substance in one kilogram of the substance is n = 5.981 mol.
The amount of substance in one gram of the substance is n = 0.006 mol.
Monoisotopic mass: 167.09462866085 Da - related to 12C91H1314N16O2.
(General information without guarantee of accuracy and completeness! The information does not replace the chemical safety data sheet or a risk assessment, but rather provides a general overview of the risk posed by the hazardous substance.
Signal word: Danger
GHS hazard statements (H phrases):
The table below lists producers and suppliers of 4-Hydroxynorephedrine as a commercial chemical for laboratories, research, industry and production with the corresponding contact details.
[0] - Specialist and research articles in scientific journals via PubMed: 4-Hydroxynorephedrine.
Last update: 2026-02-11
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